Nucleotides are the building blocks of DNA and RNA. Nucleosides are its precursors. The assembly of a nucleoside with a phosphate group results in the formation of a nucleotide and further covalent binding with several other nucleotides, a DNA or RNA molecule.
What is a nucleoside?
A nucleoside is the assembly of a nitrogenous base with a sugar, ribose in RNA and deoxyribose in DNA. The classic nucleosides are adenosine, thymidine, cytidine, guanosine or even uridine.
Nucleoside = Sugar + Nitrogenous Base
What is a nucleotide?
A nucleotide corresponds to the product of the bond between a nucleoside and a phosphate group. Common nucleotides are adenine, thymine, cytosine, guanine or even uracil.
Nucleotide = Nucleoside + Phosphate
Nucleotide = Sugar + Nitrogenous Base + Phosphate
Nucleotides therefore differ from nucleosides by the presence of a phosphate group in their structure. In addition, the name of the molecule varies between nucleotides and nucleosides.
Read Also: ADP Biology Definition And Explanations
Nucleoside vs Nucleotide
|Definition|| Nucleoside = Sugar + Nitrogenous Base |
A nucleoside consists of covalent combination of ribose, in RNA and deoxyribose in DNA, and nitrogenous base.
| Nucleotide = Sugar + Nitrogenous Base + Phosphate |
A nucleotide contains a nucleoside (sugar and nitrogenous base) and phosphate group
|Functions||Nucleosides are responsible for expressing and transferring genetic information||+ Genetic data storage|
+ Energy currency for cells in the form of ATP
+ Functions as coenzymes and regulatory chemicals
|Examples||+ Thymidine, Uridine and cytidine|
+ Guanosine and adenosine
| + Adenosine Monophosphate (AMP)|
+ Adenosine Diphosphate (ADP
+ Adenosine Triphosphate (ATP)
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